Can Chiropractic Care Influence More Than Pain? What New Research Is Exploring
Most people seek chiropractic care because of physical concerns such as back pain, neck discomfort, stiffness, or reduced movement.
But the body is an interconnected system. The spine, nervous system, muscles, and joints all work together to help us move, respond to stress, and adapt to everyday demands.
Because of this connection, researchers are increasingly interested in whether chiropractic care may influence the body in ways that go beyond simple joint movement.
A recent study explored one small part of this question by looking at changes in a saliva-based immune marker following upper cervical chiropractic care.
Read StudyA Quick Introduction to SIgA
The study focused on secretory immunoglobulin A (SIgA).
SIgA is an antibody found in saliva and other mucosal secretions in the body. It plays a role in the body’s first-line immune defences, particularly in areas such as the mouth, respiratory system, and digestive tract.
Because SIgA can be measured through saliva samples, researchers sometimes use it as a way of exploring how the nervous system, stress, and immune responses may interact.
Importantly, measuring a biomarker like SIgA does not mean a treatment is improving the immune system. It simply gives researchers a way to observe physiological responses in the body.
What the Study Looked At
The study involved 41 participants across five chiropractic clinics in North America.
Each participant provided saliva samples at three points:
• before receiving their first upper cervical chiropractic adjustment
• 30 minutes after the adjustment
• two weeks later
The researchers were interested in seeing whether the chiropractic adjustment was associated with changes in SIgA levels.
What the Researchers Found
The researchers observed a temporary increase in SIgA levels about 30 minutes after the adjustment.
However, when samples were taken two weeks later, the SIgA levels had returned close to the original baseline.
In other words, the change appeared to be short-term rather than sustained.
The study also looked at other biological markers related to inflammation and nervous system activity, but these did not show significant changes during the study period.
Participants also reported small improvements in physical and mental health scores on a standard health questionnaire over the two-week period.
Why Researchers Are Interested in This
The nervous system plays a central role in how the body responds to stress, movement, and the environment.
There is growing scientific interest in the connections between the nervous system, immune system, and endocrine system. These systems communicate with each other constantly.
Some researchers hypothesise that changes in joint movement or nervous system input from the spine could influence broader physiological responses. However, the exact mechanisms are still being studied.
Studies like this one help researchers explore these questions, but they do not provide definitive answers.
What This Means for People Receiving Chiropractic Care
For most people, chiropractic care is primarily about improving movement, comfort, and function.
However, many patients also report that they simply feel different after an adjustment. They may describe feeling:
• more relaxed
• less tense
• clearer in their thinking
• or generally more at ease in their body
Research into areas such as nervous system responses and stress-related biomarkers may help explain some of these experiences over time.
That said, it is important not to overinterpret early findings. This particular study was small and observational, meaning it cannot prove cause and effect.
The Importance of Balanced Interpretation
The authors of the study described their findings as preliminary and emphasised the need for larger studies with longer follow-up periods.
Because of the small sample size and short study duration, the results should be viewed as an early exploration rather than a clinical conclusion.
At this stage, research like this simply suggests that the body may respond in measurable ways following certain types of chiropractic care.
Chiropractic Care in Everyday Life
In practice, chiropractic care focuses on the musculoskeletal system, including how the spine and joints move and how muscles support those movements.
An assessment may look at factors such as:
• posture and spinal movement
• joint mobility
• muscle tension
• movement patterns
• daily habits and activity levels
Care is then adapted to each person’s presentation and comfort level.
For many people, this approach supports better movement and helps them stay active in daily life.
Research into chiropractic care is continuing to evolve.
Studies like this one are exploring how the body responds to spinal adjustments in ways that may involve the nervous system and other physiological processes.
While these findings are interesting, they should be interpreted cautiously and do not mean chiropractic care can treat immune conditions.
What they do highlight is the complexity of the body and the growing scientific interest in understanding how different systems interact.
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**This article discusses findings from a preliminary observational study. The research does not demonstrate that chiropractic care improves immune function or treats immune-related conditions. If you have health concerns, seek advice from a qualified healthcare professional.
Reference:
Schalow PR, Kimball KA, Schurger FT, Sooley GR, Bales SP, Rochester RP, Brooks RT, Hunt JM. Secretory Immunoglobulin A and Upper Cervical Chiropractic: A Preliminary Prospective, Multicenter, Observational Study. J Chiropr Med. 2021 Sep;20(3):121-127. doi: 10.1016/j.jcm.2021.10.003. Epub 2022 Apr 6. PMID: 35463842; PMCID: PMC9023133.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9023133/